Lion's Mane

The Focus Mushroom

Lion's Mane (Hericium erinaceus) has been used in traditional Chinese and Japanese practices for centuries, valued for its role in supporting focus and mental clarity. It was often consumed as a tea, including by monks during long periods of meditation.

Today, it is one of the most widely studied functional mushrooms for cognitive support. Modern research focuses on its bioactive polysaccharides, especially β-glucans, the most measurable marker of Lion's Mane extract quality.

Lion's Mane mushroom close-up

How Lion's Mane Works

Lion's Mane is one of the most studied functional mushrooms for cognitive support. Here is what current research suggests.

1.Bioactive polysaccharides, including β-glucans.

Lion's Mane's most well-characterized active compound class is its bioactive polysaccharides, especially β-glucans. β-glucans are studied for their role in supporting cognitive function and immune-related pathways relevant to overall brain health.

2.Antioxidant activity in the fruiting body.

The fruiting body of Lion's Mane contains antioxidant compounds studied for their role in helping the body manage everyday oxidative stress, including in neural tissue.

3.Supports the gut-brain axis.

β-glucans act as prebiotic fiber for beneficial gut bacteria, which produce short-chain fatty acids and influence neurotransmitter activity through the gut-brain axis. The gut-brain connection is increasingly recognized as central to mood and cognitive function.

4.Centuries of traditional use, decades of modern research.

Lion's Mane has been used in traditional practices for centuries and is one of the most studied functional mushrooms in modern cognitive research, with multiple human trials examining its effects on cognitive function and well-being.

Summarized from published research on Hericium erinaceus and cognitive function.

Lion's Mane fruiting body cluster

Why We Use It

DayShift is built on two layers: ingredients used for short-term cognitive support, and ingredients used for daily, compounding cognitive support. Lion's Mane is in the second layer.

We use a USDA Organic Lion's Mane fruiting body extract standardized to ≥70% β-glucans, verified by Megazyme enzymatic assay. This is one of the highest β-glucan concentrations available in the Lion's Mane category. Our extract has also been notified to the FDA as GRAS (Generally Recognized as Safe), a regulatory designation few mushroom extracts hold.

USDA Organic FDA-Notified GRAS ≥70% β-Glucans Megazyme Verified

Key Focus Areas

  • Cognitive Function
  • Memory and Recall
  • Long-Term Brain Health

Why β-Glucans Are The Metric That Matters

Lion's Mane research is built on its bioactive polysaccharides. Within that family, β-glucans are the most measurable, most verifiable, and most consistently cited marker of quality. They are what researchers track when characterizing a Lion's Mane extract, and the active most often quantified in published studies.

How The Math Works

A Lion's Mane supplement's β-glucan content depends on two things: how much extract is in the serving, and what percentage of that extract is actually β-glucans. Both numbers can be measured with a standardized lab method (Megazyme enzymatic assay) and reported on a Certificate of Analysis. Most Lion's Mane supplements never tell you their β-glucan content, usually because they have not measured it.

Source β-Glucan Content Delivered per 1,000 mg
Whole Lion's Mane powder~2 to 5%20 to 50 mg
Typical Lion's Mane extract~10%100 mg
High-end commercial extract~30%300 mg
DayShift extract≥70%≥700 mg

What This Means For DayShift's 325 mg

DayShift uses 325 mg of a Lion's Mane extract standardized to ≥70% β-glucans, USDA Organic, and FDA-notified GRAS. That delivers ≥225 mg of β-glucans per serving, the β-glucan content equivalent of approximately 2,250 mg of typical Lion's Mane extract (assuming ~10% β-glucan content, the low end of the standard industry range).

325 mg of a properly standardized extract delivers more measurable Lion's Mane actives than 2,250 mg of an unstandardized product. Concentration, not gross weight, is the measure that holds up under a lab test.

Why This Is Honest, Not Marketing

β-glucan content is verifiable. You can confirm it with the Certificate of Analysis on the ingredient. "Mg of mushroom" alone tells you nothing about how concentrated the actives are. We chose the metric that can be measured and reported, not the one that just looks big on a label.

How Our Dose Stacks Up.

A clinically researched β-glucan dose, delivered daily.

Clinical Studies
1,000 to 3,000 mg
Typical Supplement
750 mg
DayShift
2,250 mg equiv. †
from 325 mg actual

† DayShift contains 325 mg of a Lion's Mane extract standardized to ≥70% β-glucans, delivering the β-glucan content equivalent of 2,250 mg of typical Lion's Mane extract (assuming ~10% β-glucan content, the low end of the standard industry range).

Want to Learn More?

Selected peer-reviewed research on Lion's Mane (Hericium erinaceus) and cognitive function.

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325 mg of standardized Lion's Mane and clinically studied doses of seven other ingredients in every packet.

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